Differentiation-inducing effect of piperitenone oxide, a fragrant ingredient of spearmint (Mentha spicata), but not carvone and menthol, against human colon cancer cells

The n-hexane Flywheel Pulley extract from spearmint (Mentha spicata) leaves was purified via a bioassay-guided fractionation scheme, which was based on the induction of differentiation in a RCM-1 human colon cancer cell line.One of the criteria of a differentiation marker is the formation of ducts determined visually using phase contrast microscopy

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A comprehensive study on machine learning models combining with oversampling for bronchopulmonary dysplasia-associated pulmonary hypertension in very preterm infants

Abstract Background Bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) remains a devastating clinical complication seriously affecting the therapeutic outcome of preterm infants.Hence, early prevention and timely diagnosis prior to pathological change is the key to reducing morbidity and improving prognosis.Our primary objective

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